Cheap Flights from Madrid to Cartagena

Cartagena is one of the most beautiful and romantic cities in the Americas, full of colour, culture and charm. The UNESCO-listed old town is a highlight, with its cobbled streets and colonial architecture, while Getsemaní adds a more vibrant, artistic edge. Sunset boat trips to the Rosario Islands, lively salsa music and some of the best street food in Colombia all make for unforgettable experiences. Beyond the city, you’ll find the coastal beauty of Santa Marta, the wild landscapes of Tayrona National Park and more of Colombia’s stunning Caribbean coastline to explore.

Whether you're travelling for a weekend break, a long-haul adventure, or a business trip, our search pulls together real-time fares so you can compare and book in minutes. We search all trusted partners to bring you flexible ticket options including one-way, return, and multi-city routes on this popular flight corridor.

Prices on the Madrid to Cartagena route vary throughout the year. To find the best deal, try adjusting your travel dates by a day or two — even small changes can significantly lower the fare. Use the search above to explore all available options.